Preprints
Filtering by Subject: Microbiology
Running a queer- and trans-inclusive faculty hiring process
                Published: 2024-03-02
                
                Subjects: Biology, Ecology and Evolutionary Biology, Life Sciences, Microbiology
            
Queer and transgender scientists face documented systemic challenges across the sciences, and as a result have a higher attrition rate than their peers. Recent calls for change within science have emphasized the importance of addressing barriers to the success and retention of queer and trans scientists to create a more inclusive, equitable, and just scientific establishment. Crucially, we note [...]
Are microbes colimited by multiple resources?
                Published: 2024-03-02
                
                Subjects: Ecology and Evolutionary Biology, Environmental Microbiology and Microbial Ecology Life Sciences, Life Sciences, Microbiology, Systems Biology
            
Resource colimitation --- the dependence of growth on multiple resources simultaneously --- has become an important topic in microbiology due both to the development of systems approaches to cell physiology and ecology, and to the relevance of colimitation to environmental science, biotechnology, and human health. Empirical tests of colimitation in microbes suggest that it may be common in [...]
Solving the “small outbreak problem” in climate epidemiology
                Published: 2024-01-04
                
                Subjects: Climate, Diseases, Ecology and Evolutionary Biology, Entomology, Environmental Public Health, Epidemiology, Life Sciences, Microbiology, Parasitic Diseases, Public Health, Virus Diseases
            
Climate change can cause outbreaks of infectious diseases in unfamiliar locations — but how do we know which unusual outbreaks are the result of climate change? Scientists often hesitate to guess, leaving the task to journalists or the public. All of these audiences would benefit from a clear and consistent framework for thinking about causality, especially in situations where outbreaks are too [...]
Withdrawn: Datathons: fostering equitability in data reuse in ecology
                Published: 2023-10-06
                
                Subjects: Biodiversity, Biology, Environmental Microbiology and Microbial Ecology Life Sciences, Genetics, Genetics and Genomics, Genomics, Life Sciences, Microbiology
            
Duplicate of https://doi.org/10.32942/X2389Q
The untapped potential of phage model systems as therapeutic agents
                Published: 2023-07-28
                
                Subjects: Biology, Evolution, Life Sciences, Medical Microbiology, Microbiology
            
With the emergence of widespread antibiotic resistance, phages are an appealing alternative to antibiotics in the fight against multidrug-resistant bacteria. Over the past few years, many phages have been isolated from various environments to treat bacterial pathogens. While isolating novel phages for treatment has had some success for compassionate use, developing novel phages into a general [...]
Breaking the Ice: A Review of Phages in Polar Ecosystems
                Published: 2023-05-28
                
                Subjects: Biodiversity, Biology, Ecology and Evolutionary Biology, Life Sciences, Marine Biology, Microbiology
            
Bacteriophages, or phages, are viruses that infect and replicate within bacterial hosts, playing a significant role in regulating microbial populations and ecosystem dynamics. However, phages from extreme environments such as polar regions remain relatively understudied due to challenges like restricted ecosystem access and low biomass. Understanding the diversity, structure, and functions of [...]
Building a Queer- and Trans-Inclusive Microbiology Conference
                Published: 2023-05-03
                
                Subjects: Gender Equity in Education, Microbiology
            
Microbiology conferences can be powerful places to build collaborations and exchange scientific thought, but for queer and transgender (trans) scientists they can also become sources of alienation and isolation. Many conference organizers would like to create welcoming and inclusive events but feel ill-equipped to make this vision a reality, and a historical lack of representation of queer and [...]
Breaking down microbial hierarchies
                Published: 2023-03-21
                
                Subjects: Ecology and Evolutionary Biology, Life Sciences, Microbiology
            
Microbial communities that degrade natural polysaccharides are thought to have a hierarchical organization and one-way positive interactions from higher to lower trophic levels. Daniels et al. have recently shown that reciprocal interactions between trophic levels can occur and that these interactions change over the duration of a batch culture.
How do microbes grow in nature? The role of population dynamics in microbial ecology and evolution
                Published: 2023-02-25
                
                Subjects: Ecology and Evolutionary Biology, Environmental Microbiology and Microbial Ecology Life Sciences, Evolution, Life Sciences, Microbiology, Systems Biology
            
The growth of microbial populations in nature is dynamic, as the cellular physiology and environment of these populations change. Population dynamics have wide-ranging consequences for ecology and evolution, determining how species interact and which mutations fix. Understanding these dynamics is also critical for clinical and environmental applications in which we need to promote or inhibit [...]
Psychological and Cultural Factors Influencing Antibiotic Prescription
                Published: 2023-01-20
                
                Subjects: Life Sciences, Medicine and Health Sciences, Microbiology, Psychiatry and Psychology
            
Humans have been giving a selective advantage to antibiotic-resistant bacteria worldwide by inundating the environment with antimicrobials for about one century. As a result, the efficacy of antibiotics has been impaired. Antibiotic resistance is a public health problem, responsible for increases in mortality and extended stays at hospitals. Hospitals and other clinical settings have implemented [...]
Psychological and Cultural Factors Influencing Antibiotic Prescription
                Published: 2023-01-02
                
                Subjects: Biology, Economics, Geography, Life Sciences, Medicine and Health Sciences, Microbiology, Psychiatry and Psychology, Psychology, Public Health, Social and Behavioral Sciences
            
Humans have inundated the environment worldwide with antimicrobials for about one century, giving selective advantage to antibiotic-resistant bacteria. Therefore, antibiotic resistance has become a public health problem responsible for increased mortality, and extended hospital stays because the efficacy of antibiotics has diminished. Hospitals and other clinical settings have implemented [...]
When bacteria are phage playgrounds: interactions between viruses, cells and mobile genetic elements
                Published: 2022-07-01
                
                Subjects: Ecology and Evolutionary Biology, Genetics and Genomics, Life Sciences, Microbiology
            
Studies of viral adaptation have focused on the selective pressures imposed by hosts. However, there is increasing evidence that interactions between viruses, cells, and other mobile genetic elements (MGEs) are determinant to the success of infections. These interactions are often associated with antagonism and competition, but sometimes involve cooperation or parasitism. They involve mechanism [...]
Psychological and Cultural Factors Influencing Antibiotic Prescription
                Published: 2022-06-21
                
                Subjects: Bacteriology, Child Psychology, Health Psychology, Life Sciences, Medicine and Health, Medicine and Health Sciences, Microbiology, Psychiatry and Psychology, Psychological Phenomena and Processes, Psychology, Social and Behavioral Sciences, Sociology, Sociology of Religion
            
Humans have been giving a selective advantage to antibiotic-resistant bacteria worldwide by inundating the environment with antimicrobials for about one century. As a result, the efficacy of antibiotics has been impaired. Antibiotic resistance is a public health problem, responsible for increases in mortality and extended stays at hospitals. Hospitals and other clinical settings have implemented [...]
Scaling up and down: movement ecology for microorganisms
                Published: 2022-06-19
                
                Subjects: Ecology and Evolutionary Biology, Life Sciences, Microbiology
            
Movement is critical for the fitness of organisms, both large and small. It dictates how individuals acquire resources, evade predators, exchange genetic material, and respond to stressful environments. Movement also influences ecological and evolutionary dynamics at scales beyond the individual organism. However, the links between individual motility and the processes that generate and maintain [...]
A minimum data standard for vector competence experiments
                Published: 2022-06-14
                
                Subjects: Bioinformatics, Entomology, Life Sciences, Microbiology, Virology
            
The growing threat of vector-borne diseases, highlighted by recent epidemics, has prompted increased focus on the fundamental biology of vector-virus interactions. To this end, experiments are often the most reliable way to measure vector competence (the potential for arthropod vectors to transmit certain pathogens). Data from these experiments are critical to understand outbreak risk, but – [...]