Filtering by Subject: Medicine and Health Sciences
Published: 2023-03-21
Subjects: Life Sciences, Medicine and Health Sciences
Epistasis refers to how genetic interactions between some genetic loci affect phenotypes and fitness. In this study, we propose the concept “structural epistasis” to emphasize the role of the variable physical interactions between molecules located at particular spaces inside the bacterial cell in the emergence of novel phenotypes. The architecture of the bacterial cell (typically a [...]
Published: 2023-02-17
Subjects: Medicine and Health Sciences, Social and Behavioral Sciences
Previous reviews concluded that nature contact was an important coping strategy against poor mental health during the COVID-19 pandemic. However, the quality of evidence in these reviews was not sufficiently documented in terms of the risk of bias in reviewed studies. We attempted to fill this gap with a Navigation Guide systematic review and meta-analyses on the associations between nature [...]
Published: 2023-01-25
Subjects: Life Sciences, Medicine and Health Sciences, Social and Behavioral Sciences
Researchers have incentives to search for and selectively report findings that appear to be statistically significant and/or conform to prior beliefs. Such selective reporting practices, including p-hacking and publication bias, can lead to a distorted set of results being published, potentially undermining the process of knowledge accumulation and evidence-based decision making. We take stock of [...]
Published: 2023-01-20
Subjects: Life Sciences, Medicine and Health Sciences, Microbiology, Psychiatry and Psychology
Humans have been giving a selective advantage to antibiotic-resistant bacteria worldwide by inundating the environment with antimicrobials for about one century. As a result, the efficacy of antibiotics has been impaired. Antibiotic resistance is a public health problem, responsible for increases in mortality and extended stays at hospitals. Hospitals and other clinical settings have implemented [...]
Published: 2023-01-02
Subjects: Biology, Economics, Geography, Life Sciences, Medicine and Health Sciences, Microbiology, Psychiatry and Psychology, Psychology, Public Health, Social and Behavioral Sciences
Humans have inundated the environment worldwide with antimicrobials for about one century, giving selective advantage to antibiotic-resistant bacteria. Therefore, antibiotic resistance has become a public health problem responsible for increased mortality, and extended hospital stays because the efficacy of antibiotics has diminished. Hospitals and other clinical settings have implemented [...]
Published: 2022-09-23
Subjects: Diseases, Medicine and Health Sciences, Virus Diseases
The recent pandemic caused by SARS-Cov-2 has witnessed an evolving succession of variants of the virus. While the phenomenon of invasion by immunity evading variants is known for other viruses such as influenza, the dynamics of the ecological and evolutionary process in the succession is little known. Since during the Covid-19 pandemic, large scale epidemiological data were collected and made [...]
Published: 2022-08-24
Subjects: Ecology and Evolutionary Biology, Life Sciences, Medicine and Health Sciences, Neuroscience and Neurobiology, Other Ecology and Evolutionary Biology, Other Life Sciences, Pharmacology, Toxicology and Environmental Health
The urgent need for medical treatments of alcohol use disorders has motivated the search for novel molecular targets of alcohol response. Most studies exploit the strengths of lab animals without considering how these and other species may have adapted to respond to alcohol in an ecological context. Here, we provide an evolutionary perspective on the molecular and genetic underpinnings of alcohol [...]
Published: 2022-08-23
Subjects: Epidemiology, Medicine and Health Sciences, Public Health
Most spatial epidemiological studies of nature-health relationships use generalized green space measures. For instance, coarse resolution spatial data containing normalized difference vegetative index (NDVI) values are prominent despite criticisms, such as the researcher’s inability to restrain exposure estimates to public (accessible) and private (largely inaccessible) land. Non-threatening [...]
Published: 2022-08-10
Subjects: Environmental Public Health, Medicine and Health Sciences, Public Health
Numerous studies have highlighted the physical and mental health benefits of contact with nature, typically in landscapes characterized by plants (i.e., “greenspace”) and water (i.e., “bluespace”). However, natural landscapes are not always green or blue, and the effects of other landscapes are worth attention. This narrative review attempts to overcome this limitation of past research. Rather [...]
Published: 2022-08-04
Subjects: Life Sciences, Medicine and Health Sciences, Physical Sciences and Mathematics, Veterinary Infectious Diseases, Veterinary Medicine
We describe fatal phaeohyphomycosis due to Veronaea botryosa in captive White’s tree frogs (Litoria caerulea), the first confirmed report in amphibians in North America. Over 15 months, six frogs developed ulcerative dermatitis on distal extremities/ventrum, which in one animal progressed to vasculitis and necrotizing osteomyelitis. All six frogs died. Clinicopathologic findings, diagnostic [...]
Published: 2022-06-21
Subjects: Bacteriology, Child Psychology, Health Psychology, Life Sciences, Medicine and Health, Medicine and Health Sciences, Microbiology, Psychiatry and Psychology, Psychological Phenomena and Processes, Psychology, Social and Behavioral Sciences, Sociology, Sociology of Religion
Humans have been giving a selective advantage to antibiotic-resistant bacteria worldwide by inundating the environment with antimicrobials for about one century. As a result, the efficacy of antibiotics has been impaired. Antibiotic resistance is a public health problem, responsible for increases in mortality and extended stays at hospitals. Hospitals and other clinical settings have implemented [...]
Published: 2022-03-01
Subjects: Analytical, Diagnostic and Therapeutic Techniques and Equipment, Anthropology, Biological and Physical Anthropology, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Diseases, Economic History, Economics, Endocrine System Diseases, Growth and Development, Health Economics, Immune System Diseases, Labor Economics, Medicine and Health Sciences, Other Economics, Public Health, Regional Economics, Social and Behavioral Sciences
This research explores the persistent effect of the Neolithic Revolution on the evolution of life expectancy in the course of human history. It advances the hypothesis and establishes empirically that the onset of the Neolithic Revolution and the associated rise in infectious diseases triggered a process of adaptation reducing mortality from infectious diseases while increasing the propensity for [...]
Published: 2022-01-06
Subjects: Economics, Entomology, Environmental Studies, Life Sciences, Medicine and Health Sciences, Other Life Sciences, Other Medicine and Health Sciences, Public Economics, Social and Behavioral Sciences, Systems Biology
Invasive mosquitoes are an emerging ecological and sanitary issue. Many factors have been suggested as drivers or barriers to their control, still no study quantified their influence over mosquito management by local authorities, nor their interplay with local economic conditions. We assessed how multiple environmental, sanitary, and socio-economic factors affected the engagement of [...]
Published: 2021-12-21
Subjects: Ecology and Evolutionary Biology, Life Sciences, Medicine and Health Sciences, Microbiology, Other Ecology and Evolutionary Biology, Pathogenic Microbiology, Veterinary Infectious Diseases, Veterinary Medicine
Mycoplasma bovis is an economically important bacterial pathogen of cattle and bison that most commonly causes pneumonia, polyarthritis and mastitis. M. bovis is prevalent in cattle and commercial bison; however, infections in other species are rare. In early 2019, we identified M. bovis in free-ranging pronghorn (Antilocapra americana) in northeastern Wyoming, USA. Here we report on additional [...]
Published: 2021-09-11
Subjects: Life Sciences, Medicine and Health Sciences, Microbiology
Allogeneous selection occurs when an antibiotic selects for resistance to more advanced members of the same family. The mechanisms of allogenous selection are (a) collateral expansion, when the antibiotic expands the gene and gene-containing bacterial populations favoring the emergence of other mutations, inactivating the more advanced antibiotics; (b) collateral selection, when the old [...]