This is a Preprint and has not been peer reviewed. This is version 3 of this Preprint.
Functional coherence among miRNA targets: a potential metric for assessing biological signal among target prediction methods in non-model species
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Authors
Christopher Wheat 
,
Rachel A. Steward,
Yu Okamura,
Heiko Vogel,
Philipp Lehmann,
Kevin T. Roberts
Abstract
Although miRNA regulation of protein production is a likely target of adaptive evolution, high false-positive rates in the identification of mRNAs targeted by miRNAs in non-model species’ complicates interpretation of recent advances. Here we document the challenges and then outline steps for the community to address these challenges.
DOI
https://doi.org/10.32942/X2PK7B
Subjects
Biology, Ecology and Evolutionary Biology, Life Sciences
Keywords
miRNA, target detection, false-positives, functional coherence, gene set enrichment analysis
Dates
Published: 2023-11-30 04:36
Last Updated: 2023-11-30 09:36
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License
CC-By Attribution-NonCommercial-NoDerivatives 4.0 International
Additional Metadata
Language:
English
Conflict of interest statement:
None
Data and Code Availability Statement:
Open data/code are not available, will be made available upon publication
There are no comments or no comments have been made public for this article.