When homology fails: lessons from liver-fluke phylogenies

When homology fails: lessons from liver-fluke phylogenies

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Authors

Pilar Alda, Annia Alba, Nicolas Bonel

Abstract

Misaligned sequences derail evolutionary inference. Datasets from GenBank require verification of positional homology and orientation before alignment and phylogenetic analysis. Liver-fluke case studies reveal how overlooked errors skew results, underscoring the need for rigorous checks in parasitology and all molecular research.

DOI

https://doi.org/10.32942/X24D1C

Subjects

Life Sciences

Keywords

phylogenetic analysis, sequence alignment, GenBank, Fasciola hepatica, COI barcode, nad1

Dates

Published: 2025-06-12 10:22

Last Updated: 2025-06-12 10:22

License

No Creative Commons license

Additional Metadata

Conflict of interest statement:
None

Data and Code Availability Statement:
Open data/code are not available

Language:
English