STRyper: an open source macOS application for microsatellite genotyping

This is a Preprint and has not been peer reviewed. This is version 2 of this Preprint.

Add a Comment

You must log in to post a comment.


Comments

There are no comments or no comments have been made public for this article.

Downloads

Download Preprint

Authors

Jean Peccoud 

Abstract

In the context of population genetics, microsatellite markers analyzed by capillary sequencing remain useful tools for quick genotyping and low-cost studies. This contrasts with the lack of a free application to analyze chromatograms for microsatellite genotyping that is designed for population geneticists. To fill this gap, I have developed STRyper, a macOS application whose source code is published under the General Public License. STRyper only uses macOS libraries, making it very lightweight, responsive, and behaving like a modern application. Its three-pane window enables easy management, searching and viewing of chromatograms imported from .fsa and. hid files, the creation of size standards and of microsatellite marker panels (including bins). The application has unique features allowing DNA ladder and genotype correction by drag-and-drop, and the management of variations in electrophoretic conditions. STRyper is available at https://github.com/jeanlain/STRyper.

DOI

https://doi.org/10.32942/X2X01C

Subjects

Biodiversity, Bioinformatics, Molecular Genetics, Other Ecology and Evolutionary Biology

Keywords

microsatellites, capillary electrophoresis, Population genetics, graphical user interface

Dates

Published: 2023-07-29 12:15

Last Updated: 2024-02-28 18:20

Older Versions
License

No Creative Commons license

Additional Metadata

Language:
English

Data and Code Availability Statement:
https://github.com/jeanlain/STRyper