Modeling complex biological systems: Tackling the parameter curse through evolution

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Authors

paulien Hogeweg

Abstract

In this perspective paper we review a previously published evolutionary model of the lac-operon to argue and demonstrate the importance of using evolutionary methods to derive relevant parameters. We show that by doing so we can debug experimental and modeling artifacts.

DOI

https://doi.org/10.32942/osf.io/safm4

Subjects

Ecology and Evolutionary Biology, Evolution, Life Sciences, Systems Biology

Keywords

Dates

Published: 2021-02-25 23:11

Last Updated: 2021-05-05 02:00

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License

CC-By Attribution-ShareAlike 4.0 International