Preprints
Filtering by Subject: Other Pharmacology, Toxicology and Environmental Health
A review of chemical defense in harlequin toads (Bufonidae; Atelopus)
Published: 2021-11-29
Subjects: Ecology and Evolutionary Biology, Evolution, Life Sciences, Other Ecology and Evolutionary Biology, Other Pharmacology, Toxicology and Environmental Health, Pharmacology, Toxicology and Environmental Health
Toads of the genus Atelopus are chemically defended by a unique combination of endogenously synthesized cardiotoxins (bufadienolides) and neurotoxins which may be sequestered (guanidinium alkaloids). Investigation into Atelopus small-molecule chemical defenses has been primarily concerned with identifying and characterizing various forms of these toxins while largely overlooking their ecological [...]