Preprints
Filtering by Subject: Epidemiology
Mapping the potential risk of coronavirus spillovers in South and Southeast Asia
Published: 2025-03-28
Subjects: Ecology and Evolutionary Biology, Environmental Public Health, Epidemiology, Life Sciences, Public Health
Bats harbor approximately a third of known mammal viruses, including recent coronaviruses that caused pandemics. As spillover risk increases due to habitat loss and fragmentation, utilizing a OneHealth approach, we identified potential zoonotic spillover and pandemic risk hotspots in South and Southeast Asia. We used a model that estimates the risk of infectious disease emergence by incorporating [...]
Land use gradients drive spatial variation in Lassa fever host communities in the Eastern Province of Sierra Leone.
Published: 2025-02-03
Subjects: Ecology and Evolutionary Biology, Epidemiology, Life Sciences, Virus Diseases
The natal multimammate mouse (Mastomys natalensis) is the primary reservoir host of Lassa mammarenavirus (LASV), a zoonotic pathogen causing Lassa fever that is endemic to West Africa. The occurrence and abundance of this species is regulated by the human environment and biotic interactions with other small-mammal species, but these ecological drivers remain poorly understood in the regions [...]
Wildlife health perceptions and monitoring practices in globally distributed protected areas
Published: 2024-04-30
Subjects: Biodiversity, Environmental Monitoring, Epidemiology, Health Information Technology, Health Policy, Life Sciences, Natural Resources and Conservation, Recreation, Parks and Tourism Administration, Sustainability, Veterinary Preventive Medicine, Epidemiology, and Public Health
Deficits in wildlife health (WH) monitoring at protected areas (PAs) can weaken the detection of infectious diseases; physical, and chemical threats; rapid response; and assessment of health management practices, threatening biodiversity conservation and global health. However, there is a lack of baseline information regarding the local perception of wildlife, human, and livestock health [...]
Solving the “small outbreak problem” in climate epidemiology
Published: 2024-01-04
Subjects: Climate, Diseases, Ecology and Evolutionary Biology, Entomology, Environmental Public Health, Epidemiology, Life Sciences, Microbiology, Parasitic Diseases, Public Health, Virus Diseases
Climate change can cause outbreaks of infectious diseases in unfamiliar locations — but how do we know which unusual outbreaks are the result of climate change? Scientists often hesitate to guess, leaving the task to journalists or the public. All of these audiences would benefit from a clear and consistent framework for thinking about causality, especially in situations where outbreaks are too [...]
VectAbundance: a spatio-temporal database of vector observations
Published: 2023-12-22
Subjects: Entomology, Environmental Public Health, Epidemiology, Life Sciences, Zoology
Modelling approaches play a crucial role in supporting local public health agencies by estimating and forecasting vector abundance and seasonality. However, the reliability of these models is contingent on the availability of standardized, high-quality data. Addressing this need, our study focuses on collecting and harmonizing egg count observations of Aedes albopictus, obtained through ovitraps [...]
The economics of nature’s healing touch: A systematic review and conceptual framework of green space, pharmaceutical prescriptions, and healthcare expenditure associations
Published: 2023-11-07
Subjects: Epidemiology
Green spaces play a crucial role in promoting sustainable and healthy lives. Recent evidence shows that green space also may reduce the need for healthcare, prescription medications, and associated costs. This systematic review provides the first comprehensive assessment of the available literature examining green space exposure and its associations with healthcare prescriptions and expenditures. [...]
Measuring the 3-30-300 Rule to Help Cities Meet Nature Access Thresholds
Published: 2023-07-02
Subjects: Environmental Public Health, Environmental Studies, Epidemiology, Geography, Physical and Environmental Geography, Public Health, Social and Behavioral Sciences
The 3-30-300 rule offers benchmarks for cities to promote equitable nature access. It dictates that individuals should see three trees from their dwelling, have 30% tree canopy in their neighborhood, and live within 300 meters of a high-quality green space. Implementing this demands thorough measurement, monitoring, and evaluation methods. Seven data and processes exist to assess these [...]
Curated dataset of accessible and recreational parks in the U.S.: Comparison to greenspace metrics and sociodemographics
Published: 2022-08-23
Subjects: Epidemiology, Medicine and Health Sciences, Public Health
Most spatial epidemiological studies of nature-health relationships use generalized green space measures. For instance, coarse resolution spatial data containing normalized difference vegetative index (NDVI) values are prominent despite criticisms, such as the researcher’s inability to restrain exposure estimates to public (accessible) and private (largely inaccessible) land. Non-threatening [...]
Deploying Ecological Countermeasures as a Biosecurity Imperative
Published: 2021-03-08
Subjects: Animal Sciences, Biodiversity, Biology, Ecology and Evolutionary Biology, Environmental Public Health, Epidemiology, Immunity, Immunology and Infectious Disease, Immunology of Infectious Disease, Immunopathology, International Public Health, Life Sciences, Maternal and Child Health, Medicine and Health Sciences, Other Immunology and Infectious Disease, Population Biology, Public Health, Terrestrial and Aquatic Ecology, Veterinary Infectious Diseases, Veterinary Medicine, Veterinary Microbiology and Immunobiology, Veterinary Pathology and Pathobiology, Zoology
The COVID-19 pandemic has brought biosecurity to the forefront of national security policy. Land use change is a fundamental driver of zoonotic disease outbreaks, yet substantial study is yet required to unravel the mechanisms by which land use-induced spillover operates. Ecological degradation may be the 21st Century’s most overlooked security threat. Within the biosecurity context, we introduce [...]
Liberating host-virus knowledge from biological dark data
Published: 2021-01-15
Subjects: Diseases, Epidemiology, International Public Health, Medicine and Health Sciences, Organisms, Public Health
Connecting basic data about bats and other potential hosts of SARS-CoV-2 with their ecological context is critical for understanding the emergence and spread of COVID-19. However, when global lockdown started in March 2020, the world’s bat experts were locked out of their research laboratories, which, in turn, locked up large volumes of offline ecological and taxonomic data. Pandemic lockdowns [...]
Ecological Countermeasures for Pandemic Prevention: When Ecological Restoration is a Human Health Imperative
Published: 2020-12-06
Subjects: Animal Sciences, Bacteriology, Biodiversity, Biology, Ecology and Evolutionary Biology, Environmental Microbiology and Microbial Ecology Life Sciences, Environmental Public Health, Epidemiology, Immunity, Immunology and Infectious Disease, Immunology of Infectious Disease, Immunopathology, Integrative Biology, International Public Health, Life Sciences, Medicine and Health Sciences, Microbiology, Parasitology, Pathogenic Microbiology, Population Biology, Public Health, Systems Biology, Terrestrial and Aquatic Ecology, Veterinary Infectious Diseases, Veterinary Medicine, Veterinary Microbiology and Immunobiology, Veterinary Pathology and Pathobiology, Zoology
Ecological restoration should be regarded as a public health service. Unfortunately, the lack of quantitative linkages between environmental and human health has limited recognition of these principle. Advent of COVID-19 pandemic provides the impetus for the further discussion. We propose ecological countermeasures as highly targeted, landscape-based interventions to arrest the drivers of land [...]
Pathways linking biodiversity to human health: A conceptual framework
Published: 2020-09-23
Subjects: Biodiversity, Environmental Public Health, Epidemiology, Geography, Immunology and Infectious Disease, Life Sciences, Medicine and Health Sciences, Nature and Society Relations, Other Psychology, Psychology, Public Health, Social and Behavioral Sciences
Biodiversity is a cornerstone of human health and well-being. However, while evidence of the contributions of nature to human health is rapidly building, research into how biodiversity relates to human health remains limited in important respects. In particular, a better mechanistic understanding of the range of pathways through which biodiversity can influence human health is needed. These [...]